Crataeva nurvala is a commonly used herbal drug against many diseases. The hepatoprotective activity of hydroalcoholic extract of dried powder of whole plant of Crataeva nurvala was investigated in carbon tetrachloride induced hepatotoxicity rat model. Hepatotoxicity was induced in Wistar rats by intraperitoneal injection of carbon tetrachloride. Different doses were tested to decide the dose related hepatoprotective efficacy of Crataeva nurvala (400 mg/kg, 600 mg/kg, 800 mg/kg bw). The Hepatoprotective effect of these extracts was evaluated by liver function biochemical parameters (i. e. total and direct bilirubin, cholesterol, alanine aminotransaminase, asparatate aminotransaminase and alkaline phosphatase activities).In extract-treated animals, the toxicity effect of carbon tetrachloride was controlled significantly by restoration of the levels of serum bilirubin, cholesterol and enzymes as compared to the normal and standard drug silymarin-treated groups. Therefore, the results of present study support the hepatoprotective effect of Crataeva nurvala
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